** NMHU NETWORK DISTURBANCE INFORMATION **

** NMHU NETWORK DISTURBANCE INFORMATION **

Chris Stead Ph.D.

 

Chris Stead, Ph.D.

Assistant Professor of Biochemistry
Office: HSCI 236
Phone: 505-426-2035
E-mail: cstead@nmhu.edu

Education

2010-2015  Postdoctoral Fellow

Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Coxiella Pathogenesis Section

2003-2010  PhD with distinction in biomedical sciences

Medical College of Georgia

1996-2000 Master of Chemistry – Second Class, Division One

University of Manchester Institute of Science and Technology, England

Courses Taught

Biochemistry I
Biochemistry II
Biochemistry Laboratory
Chemistry for Non-Majors with laboratory
General Chemistry I with laboratory
Senior Chemistry Applications

Research Interests

My lab is investigating lipid biosynthetic pathways of the bacterium Coxiella burnetii as well as exploring the roles lipids play in C. burnetii growth and pathogenesis.

Selected Publications

  1. Stead CM, Omsland A, Beare PA, Sandoz KM, Heinzen RA. Sec-mediated secretion by Coxiella burnetii. BMC Microbiol. 2013;13(1):222.
  2. Beare PA, Gilk SD, Larson CL, Hill J, Stead CM, Omsland A, Cockrell DC, Howe D, Voth DE, Heinzen RA. Dot/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages. MBio. 2011;2(4).
  3. Stead CM, Pride AC, Trent MS, “Genetics and biosynthesis of lipid A,” in Knirel YA and Valvano MA (eds), Bacterial lipopolysaccharides: Structure, chemical synthesis, biogenesis and interaction with host cells. SpringerWienNewYork, 2011, pp. 163-194.
  4. Stead CM, Zhao J, Raetz CR, Trent MS. Removal of the outer Kdo from Helicobacter pylori lipopolysaccharide and its impact on the bacterial surface. Mol Microbiol. 2010;78(4):837-52.
  5. Rutten L, Mannie JP, Stead CM, Raetz CR, Reynolds CM, Bonvin AM, Tommassen JP, Egmond MR, Trent MS, Gros P. Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium. Proc Natl Acad Sci U S A. 2009;106(6):1960-4.
  6. Stead CM, Beasley A, Cotter RJ, Trent MS. Deciphering the unusual acylation pattern of Helicobacter pylori lipid A. J Bacteriol. 2008;190(21):7012-21.
  7. Stead C, Tran A, Ferguson D Jr, McGrath S, Cotter R, Trent S. A novel 3-deoxy-D-manno-octulosonic acid (Kdo) hydrolase that removes the outer Kdo sugar of Helicobacter pylori lipopolysaccharide. J Bacteriol. 2005;187(10):3374-83.

For a full list of publications please visit the following link: Chris Stead publications

Funding

2016        NIH/NIGMS New Mexico IDeA Networks of Biomedical Research Excellence (NM-INBRE) Focus Grant

2016        Faculty Research Committee (FRC) Research Funds